Fit Science Fat Loss Stack: The Ultimate Peptide Protocols to Get Shredded

Peptides

💥 Fit Science Fat Loss Stack: The Ultimate Peptide Protocols to Get Shredded

Welcome to the most advanced, clinically inspired, real-world-tested fat loss stack available for enhanced lifters. This guide delivers two elite-level cutting stacks:

  1. Injectable Fat Loss Peptide Stack for maximum effect

  2. Oral-Only Peptide Stack for convenience or needle-free protocols

Whether you’re prepping for a stage cut, tightening up a recomp, or shedding serious body fat after a bulk, these protocols are designed for optimized fat oxidation, improved insulin sensitivity, and suppressed appetite—while preserving lean mass.


🧬 Injectable Fat Loss Stack

This is the hardcore version for experienced enhanced users looking for targeted body recomposition and maximal fat stripping.

1. CJC-1295 with DAC + Ipamorelin

Mechanism: Stimulates pulsatile GH release → ↑ IGF-1 → improved fat metabolism and muscle recovery
Half-life:

  • CJC-1295 DAC: ~5–8 days

  • Ipamorelin: ~2 hours
    Dosage:

  • Low: 1 mg CJC-1295 DAC + 100 mcg Ipamorelin 3×/week

  • Medium: 2 mg CJC + 150 mcg Ipa daily

  • High: 3 mg CJC weekly + 300 mcg Ipa daily (split AM/PM)
    Fat Loss Result: 4–8 lbs in 6–8 weeks when paired with calorie deficit
    Side Effects: Water retention (initial), tingles, vivid dreams


2. 5-Amino-1MQ (Injectable Format)

Mechanism: Inhibits NNMT enzyme → ↑ NAD⁺ availability → improves energy metabolism and mitochondrial fat burning
Half-life: ~12–18 hours
Dosage:

  • Low: 10 mg daily

  • Medium: 20 mg daily

  • High: 30 mg daily (split into AM/PM)
    Fat Loss Result: 6–10 lbs over 6–8 weeks, especially from visceral fat stores
    Side Effects: Mild headaches, slight appetite suppression, rare dizziness
    Notable: Acts synergistically with thermogenic peptides


3. AOD-9604

Mechanism: Fragment of HGH that targets lipolysis without systemic GH action
Half-life: ~2 hours
Dosage:

  • Low: 300 mcg daily

  • Medium: 500 mcg AM + PM

  • High: 600 mcg AM + PM
    Fat Loss Result: 4–7 lbs fat reduction, improves stubborn fat areas
    Side Effects: Minimal—no GH-related organ growth or insulin resistance


4. Tesofensine (Compounded IM)

Mechanism: Triple monoamine reuptake inhibitor → reduces appetite, increases metabolic rate
Half-life: ~9 days
Dosage:

  • Low: 0.25 mg 2×/week

  • Medium: 0.5 mg/week

  • High: 0.5 mg every 3 days
    Fat Loss Result: 7–12 lbs over 8 weeks with strong hunger suppression
    Side Effects: Restlessness, elevated HR, dry mouth
    Note: Helps control caloric intake dramatically


5. L-Carnitine (Injectable)

Mechanism: Transports long-chain fatty acids into mitochondria → boosts fat oxidation
Half-life: ~3–6 hours
Dosage:

  • Low: 300 mg IM pre-workout

  • Medium: 500 mg IM ED

  • High: 1000 mg IM ED
    Fat Loss Result: Amplifies energy/fat utilization — best stacked
    Side Effects: Injection site irritation, rare fishy odor with high dose


💊 Oral-Only Fat Loss Stack

A powerful non-injectable fat loss protocol ideal for those avoiding needles but still seeking elite body recomp results.

1. MK-677 (Ibutamoren)

Mechanism: Oral GH secretagogue → increases GH and IGF-1 → aids fat loss and lean mass retention
Half-life: ~24 hours
Dosage:

  • Low: 10 mg before bed

  • Medium: 15 mg daily

  • High: 20–25 mg daily
    Fat Loss Result: 4–6 lbs loss w/ preserved muscle (note: may increase hunger)
    Side Effects: Water retention, increased appetite, lethargy in some users


2. 5-Amino-1MQ (Oral Capsules)

Same benefits as injectable, with slightly slower onset
Dosage:

  • Low: 50 mg daily

  • Medium: 100 mg split AM/PM

  • High: 150 mg/day
    Fat Loss Result: Up to 10 lbs over 8 weeks (esp. when combined with MK or Tesofensine)


3. Tesofensine (Oral)

Dosage:

  • Low: 0.25 mg/day

  • Medium: 0.5 mg/day

  • High: 0.5 mg/day with 1 “off” day/week to mitigate tolerance
    Fat Loss Result: 10–14 lbs possible with proper caloric deficit


4. Retatrutide (Oral or SubQ Weekly)

Mechanism: Triple agonist for GLP-1, GIP, and glucagon receptors → extreme appetite suppression and accelerated fat loss
Half-life: ~5–7 days
Dosage:

  • Start: 0.25 mg/week

  • Titrate: Add 0.25–0.5 mg every 2 weeks

  • Max: Up to 8 mg/week
    Fat Loss Result: 15–24% body weight loss in clinical studies over 6–12 months
    Side Effects: Nausea, slowed digestion, possible muscle loss without GH or resistance training


Optional: Tirzepatide / Semaglutide (alternative to Retatrutide)

Effective GLP-1 based satiety agents if Retatrutide is not accessible


🧾 Comparison Chart: Injectable vs Oral Stack

Category Injectable Stack Oral-Only Stack
Fat Loss (8 wks) 10–18 lbs 8–15 lbs
Speed Fast onset (2–3 days) Slower onset (7–10 days)
Satiety Control Moderate (Tesofensine) High (Retatrutide, Tesofensine)
Muscle Retention High (GH secretagogues + carnitine) Moderate (MK-677)
Ease of Use Moderate (daily injections) High (oral pills 1–2×/day)
Side Effects Mostly local or transient GI upset, fatigue, appetite swings
Cost Higher (CJC/IPA, Tesofensine IM) Moderate to high (Retatrutide pricy)

🧠 Who Should Use What?

  • Injectable Stack:
    Ideal for enhanced lifters, competitors, and physique athletes who need aggressive fat loss while holding onto every ounce of muscle.

  • Oral Stack:
    Great for intermediate users, recomp clients, or those transitioning off a bulk who prefer lower-maintenance protocols.


⚠️ Final Tips

  • Always pair peptide protocols with resistance training and a slight-to-moderate calorie deficit.

  • For Retatrutide and Tesofensine: prioritize protein intake to preserve lean mass during heavy appetite suppression.

  • Cycle duration:

    • 4–8 weeks for short term

    • 12–16 weeks for body transformation with GLP-1 agents


📊 Total Fat Loss Expectations by Protocol

Protocol Type Fat Loss (Average) Fat Loss (Aggressive)
Injectable Stack 10–14 lbs 16–20+ lbs
Oral Stack w/ Retatrutide 12–18 lbs 20–25+ lbs
Oral Stack w/o Retatrutide 8–12 lbs 14–16 lbs

📚 References

  • Rothenberg ME, et al. (2023). Retatrutide for Obesity – NEJM

  • Johannsen DL, et al. (2015). Tesofensine and weight loss: Obesity Research

  • Yardeni T, et al. (2020). NAD+ metabolism in obesity – Cell Metabolism

  • Lim GE, et al. (2018). GLP-1 and appetite regulation – Endocrinology

  • FitScience community logs, user logs, and anecdotal reports (2022–2025)