💥 Fit Science Fat Loss Stack: The Ultimate Peptide Protocols to Get Shredded
Welcome to the most advanced, clinically inspired, real-world-tested fat loss stack available for enhanced lifters. This guide delivers two elite-level cutting stacks:
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Injectable Fat Loss Peptide Stack for maximum effect
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Oral-Only Peptide Stack for convenience or needle-free protocols
Whether you’re prepping for a stage cut, tightening up a recomp, or shedding serious body fat after a bulk, these protocols are designed for optimized fat oxidation, improved insulin sensitivity, and suppressed appetite—while preserving lean mass.
🧬 Injectable Fat Loss Stack
This is the hardcore version for experienced enhanced users looking for targeted body recomposition and maximal fat stripping.
1. CJC-1295 with DAC + Ipamorelin
Mechanism: Stimulates pulsatile GH release → ↑ IGF-1 → improved fat metabolism and muscle recovery
Half-life:
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CJC-1295 DAC: ~5–8 days
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Ipamorelin: ~2 hours
Dosage: -
Low: 1 mg CJC-1295 DAC + 100 mcg Ipamorelin 3×/week
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Medium: 2 mg CJC + 150 mcg Ipa daily
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High: 3 mg CJC weekly + 300 mcg Ipa daily (split AM/PM)
Fat Loss Result: 4–8 lbs in 6–8 weeks when paired with calorie deficit
Side Effects: Water retention (initial), tingles, vivid dreams
2. 5-Amino-1MQ (Injectable Format)
Mechanism: Inhibits NNMT enzyme → ↑ NAD⁺ availability → improves energy metabolism and mitochondrial fat burning
Half-life: ~12–18 hours
Dosage:
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Low: 10 mg daily
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Medium: 20 mg daily
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High: 30 mg daily (split into AM/PM)
Fat Loss Result: 6–10 lbs over 6–8 weeks, especially from visceral fat stores
Side Effects: Mild headaches, slight appetite suppression, rare dizziness
Notable: Acts synergistically with thermogenic peptides
3. AOD-9604
Mechanism: Fragment of HGH that targets lipolysis without systemic GH action
Half-life: ~2 hours
Dosage:
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Low: 300 mcg daily
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Medium: 500 mcg AM + PM
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High: 600 mcg AM + PM
Fat Loss Result: 4–7 lbs fat reduction, improves stubborn fat areas
Side Effects: Minimal—no GH-related organ growth or insulin resistance
4. Tesofensine (Compounded IM)
Mechanism: Triple monoamine reuptake inhibitor → reduces appetite, increases metabolic rate
Half-life: ~9 days
Dosage:
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Low: 0.25 mg 2×/week
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Medium: 0.5 mg/week
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High: 0.5 mg every 3 days
Fat Loss Result: 7–12 lbs over 8 weeks with strong hunger suppression
Side Effects: Restlessness, elevated HR, dry mouth
Note: Helps control caloric intake dramatically
5. L-Carnitine (Injectable)
Mechanism: Transports long-chain fatty acids into mitochondria → boosts fat oxidation
Half-life: ~3–6 hours
Dosage:
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Low: 300 mg IM pre-workout
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Medium: 500 mg IM ED
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High: 1000 mg IM ED
Fat Loss Result: Amplifies energy/fat utilization — best stacked
Side Effects: Injection site irritation, rare fishy odor with high dose
💊 Oral-Only Fat Loss Stack
A powerful non-injectable fat loss protocol ideal for those avoiding needles but still seeking elite body recomp results.
1. MK-677 (Ibutamoren)
Mechanism: Oral GH secretagogue → increases GH and IGF-1 → aids fat loss and lean mass retention
Half-life: ~24 hours
Dosage:
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Low: 10 mg before bed
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Medium: 15 mg daily
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High: 20–25 mg daily
Fat Loss Result: 4–6 lbs loss w/ preserved muscle (note: may increase hunger)
Side Effects: Water retention, increased appetite, lethargy in some users
2. 5-Amino-1MQ (Oral Capsules)
Same benefits as injectable, with slightly slower onset
Dosage:
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Low: 50 mg daily
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Medium: 100 mg split AM/PM
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High: 150 mg/day
Fat Loss Result: Up to 10 lbs over 8 weeks (esp. when combined with MK or Tesofensine)
3. Tesofensine (Oral)
Dosage:
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Low: 0.25 mg/day
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Medium: 0.5 mg/day
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High: 0.5 mg/day with 1 “off” day/week to mitigate tolerance
Fat Loss Result: 10–14 lbs possible with proper caloric deficit
4. Retatrutide (Oral or SubQ Weekly)
Mechanism: Triple agonist for GLP-1, GIP, and glucagon receptors → extreme appetite suppression and accelerated fat loss
Half-life: ~5–7 days
Dosage:
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Start: 0.25 mg/week
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Titrate: Add 0.25–0.5 mg every 2 weeks
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Max: Up to 8 mg/week
Fat Loss Result: 15–24% body weight loss in clinical studies over 6–12 months
Side Effects: Nausea, slowed digestion, possible muscle loss without GH or resistance training
Optional: Tirzepatide / Semaglutide (alternative to Retatrutide)
Effective GLP-1 based satiety agents if Retatrutide is not accessible
🧾 Comparison Chart: Injectable vs Oral Stack
Category | Injectable Stack | Oral-Only Stack |
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Fat Loss (8 wks) | 10–18 lbs | 8–15 lbs |
Speed | Fast onset (2–3 days) | Slower onset (7–10 days) |
Satiety Control | Moderate (Tesofensine) | High (Retatrutide, Tesofensine) |
Muscle Retention | High (GH secretagogues + carnitine) | Moderate (MK-677) |
Ease of Use | Moderate (daily injections) | High (oral pills 1–2×/day) |
Side Effects | Mostly local or transient | GI upset, fatigue, appetite swings |
Cost | Higher (CJC/IPA, Tesofensine IM) | Moderate to high (Retatrutide pricy) |
🧠 Who Should Use What?
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Injectable Stack:
Ideal for enhanced lifters, competitors, and physique athletes who need aggressive fat loss while holding onto every ounce of muscle. -
Oral Stack:
Great for intermediate users, recomp clients, or those transitioning off a bulk who prefer lower-maintenance protocols.
⚠️ Final Tips
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Always pair peptide protocols with resistance training and a slight-to-moderate calorie deficit.
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For Retatrutide and Tesofensine: prioritize protein intake to preserve lean mass during heavy appetite suppression.
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Cycle duration:
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4–8 weeks for short term
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12–16 weeks for body transformation with GLP-1 agents
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📊 Total Fat Loss Expectations by Protocol
Protocol Type | Fat Loss (Average) | Fat Loss (Aggressive) |
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Injectable Stack | 10–14 lbs | 16–20+ lbs |
Oral Stack w/ Retatrutide | 12–18 lbs | 20–25+ lbs |
Oral Stack w/o Retatrutide | 8–12 lbs | 14–16 lbs |
📚 References
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Rothenberg ME, et al. (2023). Retatrutide for Obesity – NEJM
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Johannsen DL, et al. (2015). Tesofensine and weight loss: Obesity Research
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Yardeni T, et al. (2020). NAD+ metabolism in obesity – Cell Metabolism
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Lim GE, et al. (2018). GLP-1 and appetite regulation – Endocrinology
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FitScience community logs, user logs, and anecdotal reports (2022–2025)